/siteworx/ was not found on this server

Is there a way to get the /siteworx/ and /nodeworx/ to work again? Like if we did the following:

https://cp2.domain.com/siteworx/?domain=test.com it will give us a:

Same would happen to Nodeworx as well - It works fine on one of our other interworx installations but not this one. We have to physically put in the port numbers such as:

https://cp2.domain.com:2443/siteworx/?domain=testing.com for it to load the login page.